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New paper on peptoid-porphyrin conjugates

posted Oct 31, 2017, 3:36 PM by Vincent Voelz
Our collaborative work with the Jiwon Seo group has just been published!  The new manuscript, "Control of porphyrin interactions via structural change of peptoid scaffold", describes a helical peptoid scaffold that can be functionalized by conjugating porphyrin groups at specific positions.  Using a combination of experiment and molecular modeling, we show that a more rigid peptoid-porphyrin linker results in improved conformational properties.   These studies move a step closer to designing foldameric molecules that can mimic the light-harvesting photosynthetic complexes found in nature. 

Woojin Yang, Boyeong Kang, Vincent A. Voelz, Jiwon Seo, Org. Biomol. Chem. (2017) doi:10.1039/C7OB02398G